Fig. 5From: Macrophage heterogeneity and its interactions with stromal cells in tumour microenvironmentMacrophages are involved in neuro-immune interactions to promote tumour progression. a Neurons induce M2 polarization and VEGF secretion of TAMs mediated by β-adrenergic signalling, contributing to tumour angiogenesis. b Monocytes are recruited towards TME CL2 cells derived from Schwann cells and differentiate into TAMs to promote nerve invasionBack to article page