Fig. 2
From: CRISPR/Cas9 mediated Y-chromosome elimination affects human cells transcriptome
Differential transcriptome analysis between ARPE-19 WT and ARPE-19 Y-depleted cell lines. Volcano plots representing regulated genes in the two conditions. Significantly differentially expressed genes (P ≤ 0.05 of Benjamini–Hochberg correction of nominal P-values obtained from the applied two-sided Wald test). Top up- and down-regulated genes are indicated in both volcanos. A Representation of DE PCGs. Significantly differentially expressed genes are shown in red. B Representation of DE lncRNAs. Significantly differentially expressed genes are shown in purple