- Talazoparib loading efficiency is defined as the moles of talazoparib loaded into the nanoparticle divided by the moles of talazoparib added to the nanoparticle synthesis reaction. # talazoparib per NP is defined as the molecules of talazoparib divided by the number of nanoparticles. PIC conjugation efficiency is defined as the moles of BPD conjugated to the nanoparticle divided by the moles of BPD added to the initial conjugation reaction. # PIC per NP is defined as the molecules of PIC (based on antibody) divided by the number of nanoparticles. Each datapoint is mean ± standard error of the mean, representative of at least four individual nanoparticle batches.
