Table 4 The inflammatory regulation of IFN-I signaling in the NF-κB pathway
From: The crucial regulatory role of type I interferon in inflammatory diseases
Study | Types of IFN-I | Target of action | Stimuli | Experimental models | Effect | Diseases |
|---|---|---|---|---|---|---|
Sermersheim et al. 2020 [178] | IFN-β | RYR and NF-κB | MG53 | MG53 knockout mice | Anti-inflammatory | Not given |
Lee et al. 2021 [179] | IFN-β | PKR and NF-κB | nc886 | HEp-2 cells | Anti-inflammatory | Not given |
Dong et al. 2023 [180] | IFN-α | PKA/CREB/NF-κB | A2AR | PI-IBS mouse models | Pro-inflammatory | PI-IBS |
Zhang et al. 2019 [181] | IFN-β | TRAF 6 | miR-146a | A549 cells | Anti-inflammatory | Viral infection |
Chen et al. 2023 [182] | IFN-β | TRAF 6 | USP47 | Mouse peritoneal macrophages | Anti-inflammatory | Viral infection |