Knocking out Fkbp51 decreases CCl4-induced liver injury through enhancement of mitochondrial function and Parkin activity

Table 3 GO analysis predicted functional alterations in Fkbp51 KO after CCl₄-induced liver injury

Function	Category	p-value		z-Score
Cellular Movement	Cell movement	3.75E−16	Decreased	− 4.673
Cell-To-Cell Signaling and Interaction	Activation of cells	5.45E−10	Decreased	− 4.262
Cellular Function and Maintenance, Inflammatory Response	Phagocytosis	2.21E−06	Decreased	− 3.891
Inflammatory Response	Immune response of cells	1.28E−07	Decreased	− 3.799
Amino Acid Metabolism, Small Molecule Biochemistry	Metabolism of amino acids	4.33E−07	Increased	2.185
Lipid Metabolism, Small Molecule Biochemistry	Conversion of lipid	5.63E−07	Increased	2.312
Organismal Survival	Morbidity or mortality	1.12E−13	Increased	2.442
Organismal Survival	Organismal death	4.81E−13	Increased	2.514

ISSN: 2045-3701