Table 2 Identified disease and function categories and involved regulators when comparing Fkbp51 KO and WT after CCl4-induced liver injury
Top regulator effect networks | ||
|---|---|---|
Regulators | Disease and function | Consistency score |
Akt, APOE, C5, CSF1, CSF2, Ige, IL1, IL17A, IL1A, IL2, KIT | Engulfment of myeloid cells | 43.7 |
Alpha catenin, AR, CSF2, EGFR, FOXA1, GLIS2, IL17A, IL2 | Endocytosis, Engulfment of cells | 21.1 |
ACOX1, CREBBP, CSF2, IFI16, IL17A, IL2, OSM, PRKCA, ROCK2 | Arteriosclerosis, Endocytosis, Engulfment of cells | 12 |
Akt, Brd4, CSF2, F2, IL17A, KITLG, PRKCD, TLR4 | Activation of antigen presenting cells, Endocytosis | 20 |