Fig. 6
From: A gene signature linked to fibroblast differentiation for prognostic prediction of mesothelioma
The prediction of regulatory mechanism in each subtype. A The regulatory networks of each MESO subtype, containing critical FDGs (blue circles), TFs (yellow circles), pathways (red circles), immune cells (blue-green circles), immune components (brown circles), and RPPA (green circles). The red lines between circles signaled positive correlation and the blue ones symbolized negative correlation with p < 0.0001. B The co-expression heatmaps reveal the interrelationship between components in each regulatory network. C The ATAC-seq results of the FDGs in the regulatory networks. D The violin plots demonstrated the IC50 distribution of the predicted 24 inhibitors among 3 different subtypes