Fig. 2
From: A gene signature linked to fibroblast differentiation for prognostic prediction of mesothelioma
Identification and features’ capture of fibroblast subtypes in MESO environment. A The tSNE plot of fibroblasts which were identified in the MESO environment in the last step. B Recognition of seven fibroblast clusters and six fibroblast subtypes (IGF_FIB, KRT19_FIB, LARP6_FIB, MMP2_FIB, MYL9_FIB and PTPRC_FIB) in the tSNE analysis. C The expression levels of four classic cell markers (DCN, COL1A2, PTPRC and APOE) and proportion of the three samples in each fibroblast subtype. D The top four or five differentially expressed genes in each fibroblast subtype. E The cell communication network of fibroblast subtypes. F The prediction of the interactions between each fibroblast subtype based on the ligand-receptor interactions. G The heatmap of pathway enrichment conditions of the six fibroblast subtypes based on GSEA analysis