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Fig. 1 | Cell & Bioscience

Fig. 1

From: Uncoupling p38α nuclear and cytoplasmic functions and identification of two p38α phosphorylation sites on β-catenin: implications for the Wnt signaling pathway in CRC models

Fig. 1

p38α is a molecular partner of the cytoplasmic β-catenin destruction complex. Co-immunoprecipitation assays showing that endogenous p38α is a molecular partner of APC, Axin1, β-catenin, and GSK3β in normal colon tissue from C57BL/6 mice and HCT-116 CRC cells. Input corresponds to 10% of the lysate. Anti-IgGs were used as negative controls. Results are representative of at least three independent experiments

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