Fig. 2

Anti-autism medication rescued Nell-1^+/6R mice from autism spectrum disorder-like behaviors. A Marble burying test: three-month-old Nell-1^+/6R  mice and their WT littermates with or without intraperitoneal injections were tested. Data are presented as median 95% ± confidence interval; n  = 15 for each group. B Three-chamber social interaction test: percentage of total test time interaction with either an unfamiliar WT mouse (mouse cup) or an inanimate object (empty cup). Three-month-old Nell-1^+/6R  mice and their WT littermates were tested with or without intraperitoneal injections. Data are presented as median ± 95% confidence interval, n  = 12 for each group. Mann-Whitney U test was used for statistical analysis. N.S .: none statistically significant. ***: P  < 0.005