Fig. 2

Differential interactome of tau, α/ꞵ synuclein, and PrP protein identified by co-immunoprecipitation combined with mass spectrometry analysis in HeLa cells. A A Venn diagram is showing unique and shared proteins in all three bait proteins identified under oxidative stress stimuli. B Gene ontology (GO) analysis in the domain of ‘’Biological Process (BP)’’ from ShinyGO webtool, in all three, bait proteins. The significance of the gene ontology enrichment is represented by the negative logarithm of the FDR (FDR < 0.05). The blue highlighted terms are shared between tau and PrP interactome and the red highlighted terms are between tau and synuclein interactome