Fig. 4From: Sex-dependent neuronal effects of α-synuclein reveal that GABAergic transmission is neuroprotective of sleep-controlling neuronsα-synM induces significant changes in the firing frequency in neurons recorded within LDTF. (A) Representative examples of current-clamp recordings of LDT neurons in which action potentials were induced by holding the cell at -45 mV under control conditions (top) and in presence of α-synM. (bottom). (B) The reduction in firing frequency induced by α-synM was significant as shown in the bar graphs depicting the average firing rate from the population of recorded LDTF neurons (n = 3; p = 0.0498; Paired T-test). LDTF: Laterodorsal tegmental nucleus of female * Indicates p < 0.05Back to article page