Fig. 6
From: SOX9 is a key component of RUNX2-regulated transcriptional circuitry in osteosarcoma
![Fig. 6](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs13578-023-01088-2/MediaObjects/13578_2023_1088_Fig6_HTML.png)
JMJD1C is required for the growth of OS in vivo. A, Immunoblotting showing knockdown of JMJD1C in SAOS2 cells. B, Image of SAOS2 xenografts. C, Tumor weight of SAOS2 tumors. p-values are from the Mann–Whitney test. D, Tumor-free survival of NSG mice bearing SAOS2 xenografts. p-values are from the log-rank (Mantel-Cox) test. E, IHC images showing Ki-67 and cleaved caspase 3 staining in SAOS2 xenografts. F and G, Quantitative analyses of Ki-67 (F) and cleaved caspase-3 (G)