Fig. 7
From: Zinc ferrite nanoparticle-induced cytotoxicity and oxidative stress in different human cells
Zinc ferrite NPs induced apoptotic response in A431, HepG2 and A549 cells. a Regulation of mRNA levels of apoptotic genes in all the cells after exposure to zinc ferrite NPs at a concentration of 20 µg/ml for 24 h. The mRNA levels were determined by quantitative real-time PCR as described in “Methods” section. b Activity of caspase-3 and caspase-9 enzymes in A431, HepG2 and A549 cells after exposure to zinc ferrite NPs at a concentration of 20 µg/ml for 24 h. Data represented are mean ± SD of three identical experiments made in three replicate. *Significant difference as compared to the controls (p < 0.05 for each)