Table 1 Classification of nuclear hormone receptors

Androgen receptor

AR

testosterone, flutamide

Estrogen receptor, alpha and beta

ERα, β

estrogens, tamoxifen, raloxifene

Glucocorticoid receptor

GR

glucocorticoidl, dexamethasone, RU486

Mineralocorticoid receptor

MR

aldosterone, spirolactone

Progesterone receptor

PR

progesterone, medroxyprogesterone acetate, RU486

Constitutive and rostane receptor

CAR

androstane

Farnesoid X receptor

FXR

bile acids, Fexaramine

Liver X receptor, alpha and beta

LXRα, β

oxysterols, T0901317, GW3965

Peroxisome proliferator-activated receptor alpha

PPARα

fibrates

Peroxisome proliferator-activated receptor beta/delta

PPARβ/δ

fatty acids

Peroxisome proliferator-activated receptor gamma

PPARγ

prostaglandins

Pregnane X receptor

PXR

xenobiotics

Retinoid A receptor, alpha, beta and gamma

RARα, β, γ

all-trans retinoic acid

Thyroid hormone receptor, alpha and beta

TRα, β, γ

thyroid hormone

Vitamin D receptor

VDR

vitamin D

Chicken ovalbumin upstream promoter-transcription factor I

COUP-TFI

n/a

Chicken ovalbumin upstream promoter-transcription factor II

COUP-TFII

n/a

V-erbA-related receptor

EAR-2

n/a

Germ cell nuclear factor

GCNF

n/a

Hepatocyte nuclear factor-4, alpha and gamma

HNF4α, γ

Fatty acids

Photoreceptor cell-specific nuclear receptor

PNR

9-cis retinoic acids

Retinoid X receptor, alpha, beta and gamma

RXRα, β, γ

9-cis retinoic acids

Testicular receptor 2

TR2

n/a

Testicular receptor 4

TR4

n/a

Homologue of the Drosophila tailless gene

TLX

n/a

Estrogen-related receptor alpha, beta and gamma

ERRα, β, γ

9-cis retinoic acid

Liver receptor homolog-1

LRH-1

phosphatidylinositols

Nerve Growth factor IB

NGFIB

n/a

Neuron-derived orphan receptor 1

NOR1

N/As

Nuclear receptor related 1

NURR1

N/A

Rev-ErbA, alpha and beta

Rev-Erbα, β

heme

RAR-related orphan receptor, alpha, beta and gamma

RORα, β, γ

cholesterol, all-trans retinoic acids

Steroidogenic factor 1

SF1

phosphatidylinositols

Dosage-sensitive sex reversal, adrenal hypoplasia critical region, on chromosome X, gene

DAX

n/a

Small heterodimer partner

SHP

n/a