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Table 1 List of DNA inserts from screen colonies

From: Systematic analysis of secreted proteins reveals synergism between IL6 and other proteins in soft agar growth of MCF10A cells

total inserts

% of all inserts

protein

Protein family

Description

Role in Breast cancer

68

6.9%

WFDC13

WFDC

WAP Four-Disulfide Core Domain 13

no

36

3.6%

PON1

PON

Paraoxonase 1

no

31

3.1%

Wnt3

Wnt

Wingless-type MMTV Integration Site Family, Member 3

[7]

18

1.8%

FGFBP2

FGFBP

Fibroblast Growth Factor Binding Protein 2

no

15

1.5%

IL6

Interleukin

Interleukin 6 (Interferon, Beta 2)

[10]

15

1.5%

FGF14

FGF

Fibroblast Growth Factor 14

no

14

1.4%

SAA1

SAA

Serum Amyloid A1

[24]

14

1.4%

PTHLH

PTHLH

Parathyroid Hormone-Like Hormone

[23]

13

1.3%

FGF10

FGF

Fibroblast Growth Factor 10

[6]

12

1.2%

LYNX1

Ly-6

Ly6/Neurotoxin 1

No

12

1.2%

IL21

Interleukin

Interleukin 21

Refs in [38]

11

1.1%

IL22

Interleukin

Interleukin 22

[16]

10

1.0%

WFDC14

WFDC

Peptidase Inhibitor 3, Skin-Derived (SKALP)

no

10

1.0%

SUMF1

SUMF

Sulfatase Modifying Factor 1

no

10

1.0%

FGF1

FGF

Fibroblast Growth Factor 1 (acidic)

[22]

  1. The most recurrent DNA inserts recovered from screen colonies are listed, with indication of the protein family they belong to, and publications linking the proteins to breast cancer development.